Mrs. Look up Mrs. at
1580s, abbreviation of mistress (q.v.), originally in all uses of that word. The plural Mmes. is an abbreviation of French mesdames, plural of madame, used in English to serve as the plural of Mrs., which is lacking. Pronunciation "missis" was considered vulgar at least into 18c. (cf missus). The Mrs. "one's wife" is from 1920.